Small Molecules

"... the KinExA results demonstrate that congener specificity is an intrinsic property of S2B1 and does not require weaker binding haptens. KinExA also provided new information on the percentage of active binding sites, valence, and effects of buffer, solvent, and biotinylation on S2B1."
Chiu YW, et al. 2001. Selective binding of polychlorinated biphenyl congeners by a monoclonal antibody: analysis by kinetic exclusion fluorescence immunoassay. Anal Chem. 73(22):5477-84.​ https://www.ncbi.nlm.nih.gov/pubmed/11816577

 Small Molecule References

  • Felix S, et.al. 2015. Structure-guided residence time optimization of a dabigatran reversal agent. mAbs. 7(5): 871-880. https://www.ncbi.nlm.nih.gov/pubmed/26047352

  • Luginbuhl B, et. al. 2006. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. J. Mol. Biol. 363(1): 75-97.  https://www.ncbi.nlm.nih.gov/pubmed/16962610
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  • Chiu YW, et al. 2001. Selective binding of polychlorinated biphenyl congeners by a monoclonal antibody: analysis by kietic exclusion fluorescence immunoassay. Anal Chem. 73(22):5477-84. https://www.ncbi.nlm.nih.gov/pubmed/11816577
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  • Blake, DA, et al. 1996. Metal binding properties of a monoclonal antibody directed toward metal-chelate complexes. J Biol Chem 271(44):27677-27685. https://www.ncbi.nlm.nih.gov/pubmed/8910359